课题组教师:

(1)刘建国(博士、教授、课题组长)
1999年本科毕业于曲阜师范大学,2004年研究生毕业于中科院山西煤化所,2006-2007年于英国牛津大学访学一年,2014-2015年于加拿大蒙特利尔大学访学一年。2013年破格晋升教授。
 办公电话:0532-86981566    E-mail:jianguoliu@upc.edu.cn     QQ:2787750886
2)曲剑波(博士、副教授)
1996年本科毕业于抚顺石油学院,2005年研究生毕业于四川大学,2009年博士毕业于中科院过程工程研究所。2009年7月于中国石油大学参加工作,2015-2016年国家公派去澳大利亚新南威尔士大学CAMD访学一年。
 办公电话:0532-86981133    E-mail:jbqu@upc.edu.cn             QQ:185994432
(3)郗丽君(博士、讲师)
2000-2007年本科、硕士就读于山东农业大学,2012年博士毕业于中科院微生物研究所。2007年加入中国石油大学生物工程与技术中心。
 办公电话:0532-86981133    E-mail:xilj@upc.edu.cn               QQ:744195766
4李静(博士、讲师)
1997-2006年,本硕博就读于中国海洋大学,2006年于中国石油大学参加工作。
 办公电话:0532-86981133    E-mail:lijing@upc.edu.cn            QQ:57860158


课题组研究生:
在读研究生

入学年份姓名本科院校入学年份姓名本科院校
2015乔能虎山东科技大学2017苏石晶河北科技大学
2015王玲玲齐鲁工业大学2017王佳宇山西农业大学
2015李士海青岛大学2017韩丹阳青岛农业大学
2016魏胜男滨州学院2017王明齐鲁工业大学
2016孟维康河北农业大学2017窦珂齐鲁工业大学
2016刘德健鲁东大学2017古红亮齐鲁工业大学
2016刘源中国石油大学2017荆亚楠齐鲁工业大学
2016张静静齐鲁工业大学2017李丹丹齐鲁工业大学
2016徐雅妍齐鲁工业大学2017沈阳齐鲁工业大学


已毕业研究生

毕业年份姓名工作单位毕业年份姓名工作单位
2009杨  娟青岛安邦炼化2014邵荟荟山东省产品质检
2010张志强衡水学院/教师2015张  瑜大连理工/博士生
2011王晶冰清华大学/博士后2015陈  伟烟台杰瑞集团
2011孙秀会东营设计院2015杨杏娜烟台东诚药业
2012刘  婧中石化管道储运2015宦关生山东新和成药业
2012王  萌临沂市/政府公务员2015陈艳丽上海微谱技术
2012尹萌萌鲁西化工2016李  伟青岛金石教育
2012靖广伦天津雷普金属材料2017徐玉良复旦大学/博士生
2012张晓晓胜利油田大明集团2017姚传凯烟台澳斯邦生物
2013陈长珍山东金诚石化2017黄雅琪待考事业编
2013张学芳历山学院/教师2017李康康康龙化成新药
2013王  瑾莱阳市农业局2017刘俊毅山东新和成药业
2014杨  波中国航空油料集团


注:① 王晶冰为博士毕业生,其余为硕士毕业生;② 部分单位名称为简写。

研究方向:
(1)功能酶的异源表达、分离纯化及结构性质研究
 (2)膜技术在生物分离、蛋白质复性及生物反应器设计中的应用
 (3)超大孔快流速新型生化分离介质的制备及应用
 (4)智能型单羟基硼酸高分子的设计及其在生物传感/生物燃料电池中的应用
 (5)功能性嵌段聚合物的制备及其自组装研究
 (6)微生物的多样性、生态功能及其在环境治理中的应用
 (7)微生物在新能源与可再生资源开发中的应用研究


承担项目情况:
国家自然科学基金项目
 (1)基于磷脂纳米盘(Nanodiscs)体系的G 蛋白偶联受体激活过程的构象变化研究(面上项目)
 (2)膜蛋白光系统I(Photosystem I)的超滤分离过程研究(面上项目)
 (3) 利用ATRP反应制备双孔道快流速生物分离介质及其性能研究(面上项目)
 (4)利用荷电效应分离纯化G蛋白偶联受体的膜过程研究(青年基金)
 (5)活性污泥中稀有微生物类群BFB的多样性及其环境响应研究(青年基金)
 (6)海水养殖环境中氨氧化功能菌群的分子生态及定量研究(青年基金)
 (7)单羟基硼酸聚合物的温度响应性质研究(青年基金)
省部级科研项目
 (8)新型双孔道超大孔生物分离介质的制备及其快速分离性能研究
 (9)活性污泥膨胀微生物的环境响应机制研究
 (10)海水养殖环境中氨氧化细菌和古菌的分子生态学研究
 (10)利用荷电效应分离纯化人趋化因子受体的膜过程研究
 (11)微生物重质油开采和脱硫的应用开发研究
 (12)亲水性超大孔聚苯乙烯生物分离介质的制备
 (13)一种新型智能型硼酸高分子材料的开发
其他纵向课题
 (14)膜技术在生物分离中的应用基础研究
 (15)超氧化物岐化酶的结构变化及其金属识别机理研究
 (16)环境响应型超大孔生物分离介质的制备及其性能研究
 (17)油藏微生物的群落结构研究和种质资源开发
 (18)活性污泥膨胀微生物的环境响应机制研究
 (19)油藏中代表细菌微进化和适应机理研究
企业横向课题
 (20)胶原蛋白出口产品的浓缩及脱盐
 (21)大豆浓缩蛋白替代鱼粉对海鲈生长、肌肉品质及肠道微生物菌群的影响
 (22)采出液的RFLP分析


论文发表情况:(2010年至今,中国石油大学为第一署名单位)
(1) Jianguo Liu, Juan Yang, Hai Xu, Junren Lu, Zhanfeng Cui. A new membrane based process to isolate immunoglobulin from chicken egg yolk. Food Chemistry2010, 122: 747-752.
 (2) Jingbing Wang, Jianguo Liu, Jianren Lu, Zhanfeng Cui. Isolation and purification of superoxide dismutase from garlic using two-stage ultrafiltration. Journal of Membrane Science2010, 352: 231-238.
 (3) Jing Li, Lu Zhang, Kangsen Mai, Chunxiao Zhang, Huitao Li, Qingyuan Duan, Hongming Ma, Shixuan Zheng. Potential of several protein sources as fish meal substitutes in diets for large yellow croaker, Pseudosciaena crocea R. Journal of World Aquaculture Soceity2010, 41(2): 278-283.
 (4) Hongyue Dang, Jing Li, Ruipeng Chen, Lin Wang, Lizhong Guo. Diversity, abundance and spatial distribution of sediment ammonia-oxidizing Betaproteobacteria in response to environmental gradients and coastal eutrophication in Jiaozhou Bay, China. Applied and Environmental Microbiology2010, 76(14): 4691-4702.
 (5) Jianguo Liu, Mengmeng Yin, Meng Wang, Xuefang Zhang, Baosheng Ge, Shuang Liu, Janren Lu, Zhanfeng Cui. A novel membrane based process to isolate photosystem-I membrane complex from spinach. Photosynthesis Research2011, 107: 187-193.
 (6) Jianguo Liu, Mengmeng Yin, Hu Zhu, Jianren Lu, Zhanfeng Cui. Purification and characterization of a hyperthermostable Mn-superoxide dismutase from Thermus thermophilus HB27. Extremophiles2011, 15: 221-226.
 (7) Jianguo Liu, Jingbing Wang, Mengmeng Yin, Hu Zhu, Jianren Lu, Zhanfeng Cui. Purification and characterization of superoxide dismutase from garlic. Food and Bioproducts Processing2011, 89: 294-299.
 (8) Jianguo Liu, Jianren Lu, Zhanfeng Cui. Enzymatic hydrolysis of cellulose in a membrane bioreactor: assessment of operating conditions. Bioprocess and Biosystems Engineering2011, 34: 525-532.
 (9) Jianguo Liu, Zhiqiang Zhang, Zhiqiang Liu, Hu Zhu, Hongyue Dang, Jianren Lu, Zhanfeng Cui. Production of cold-adapted amylase from marine bacterium Wangia sp. C52. Marine Biotechnology2011, 13: 837-844.
 (10) Jianbo Qu, Yongdong Huang, Guanglun Jing, Jianguo Liu, Weiqing Zhou, Hu Zhu, Jianren Lu. A novel matrix derivatized from hydrophilic gigaporous polystyrene-based microspheres for high-speed immobilized-metal affinity chromatography. Journal of Chromatography B2011, 879: 1043-1048.
 (11) Lijun Xi, Limin Zhang, Jisheng Ruan, Ying Huang. Nonomuraea maritima sp. nov., isolated from coastal sediment. International Journal of Systematic and Evolutionary Microbiology2011, 61: 2740-2744.
 (12) Jianguo Liu, Xuefang Zhang, Meng Wang, Jing Liu, Meiwen Cao, Jianren Lu, Zhanfeng Cui. Characterization of photosystem I from spinach: effect of solution pH. Photosynthesis Research 2012, 112: 63-70.
 (13) Jianguo Liu, Jing Liu, Xuefang Zhang. Production and characterization of ovalbumin and ovotransferrin from chicken egg white. International Journal of Food Engineering 2012, 8: 1-12.
 (14) Jianbo Qu, Huihui Shao, Juan Li, Guanglun Jing, Jianguo Liu, Weiqing Zhou. Hydrophilization of gigaporous polystyrene microspheres with saccharide as high-speed protein chromatography base support. Reactive and Functional Polymers2012, 72: 606-612.
 (15) Jianbo Qu, Huihui Shao, Xiaoxiao Zhang. Atom transfer radical polymerization of 3-O-methacryloyl-diacetone-D-glucose. Applied Mechanics and Materials2012, 189: 3-6.
 (16) Jianguo Liu, Bo Yang, Changzhen Chen. A novel membrane based process to isolate peroxidase from horseradish roots: optimization of operating parameters. Bioprocess and Biosystems Engineering2013, 36: 251-257.
 (17) Jianguo Liu, Changzhen Chen, Baosheng Ge, Jianren Lu, Zhanfeng Cui. A novel membrane based process to isolate recombinant human chemokine receptor CCR3 produced in Escherichia coli. Journal of Membrane Science2013, 425: 98-104.
 (18) Jianbo Qu, Huihui Shao, Guanglun Jing, Fang Huang. PEG-chitosan-coated iron oxide nanoparticles with high saturated magnetization as carriers of 10-hydroxycamptothecin: preparation, characterization and cytotoxicity studies. Colloids and Surfaces B2013, 102: 37-44.
 (19) Jianguo Liu. Effect of solution pH on partial properties of photosystem II from spinach. Research Journal of Biotechnology 2014, 9(6): 81-84.
 (20) Jianbo Qu, Guansheng Huan, Yanli Chen, Weiqing Zhou, Jianguo Liu, Fang Huang. Coating gigaporous polystyrene microspheres with cross-linked poly(vinyl alcohol) hydrogel as a rapid protein chromatography matrix. ACSApplied Materials & Interfaces2014, 6(15): 12752-12760.
 (21) Jianbo Qu, Yanli Chen, Guansheng Huan, Weiqing Zhou, Jianguo Liu, Hu Zhu, Xiaoyun Zhang. Preparation and characterization of a thermoresponsive gigaporous medium for high-speed protein chromatography. Analytica Chimic Acta2015, 853(1): 617-624.
 (22) Wenming Wan, Peng Zhou, Fei Cheng, Xiaoli Sun, Xinhu Lu, Kangkang Li, Hai Xu, Miao Sun, Frieder Jäkle. Thermo-responsive behavior of borinic acid polymers: experimental and molecular dynamics studies. Soft Matter 2015, 11: 7159-7164.
 (23) 曲剑波,陈艳丽,宦关生,周炜清,张晓云. 一种温敏型超大孔生物分离介质的制备及表征. 高分子学报2015, 1: 57-64.
 (24) Jianbo Qu, Yuliang Xu, Junyi Liu, Jingbin Zeng, Yanli Chen, Weiqing Zhou, Jianguo Liu. Thermo- and pH-responsive polymer brushes-grafted gigaporous polystyrene microspheres as a high-speed protein chromatography matrix. Journal of Chromatography A2016, 1441: 60-67.
 (25) Jianbo 
Qu, Yuliang Xu, Junyi Liu, Shihai Li, Weiqing Zhou, Jianguo Liu. Chemical coating polysaccharide on gigaporous polystyrene microspheres as a high-speed protein chromatography matrix, Polymer Engineering and Science 2016, 56(12): 1407-1414.
 (26) 徐玉良,曲剑波,王晓娟,刘俊毅,李士海,刘建国. 一种聚苯乙烯荧光微球的制备及发光机理研究. 高分子学报 2016, 10: 1368-1373.
 (27) Lingling Wang, Yaqi Huang, Xuefang Zhang, Jianbo Qu, Jianguo Liu. Characterization of photosystem I and photosysyem II from spinach: effect of ionic strength and impact on purification. Progress in Biochemistry and Biophyscis2016, 43(9): 895-902.
 (28) Lijun Xi, Nenghu Qiao, Zhencong Zhang, Laihong Yan, Fengbo Li, Jinpeng Hu, Jing Li. Sinorhodobacter hungdaonensis sp. nov. isolated from activated sludge collected from a municipal wastewater treatment plant. Antonie van Leeuwenhoek2016, 1-6.
 (29) Lijun Xi, Zhencong Zhang, Nenghu Qiao, Yu Zhang, Jing Li, Jingyi Zhao, Zijun Xiao. Complete genome sequence of the novel thermophilic polyhydroxyalkanoates producer Aneurinibacillus sp. XH2 isolated from Gudao oilfield in China. Journal of Biotechnology2016, 227: 54-55.  
 (30) Xiaoli Sun, Dongming Liu, Xinhu Lu, Peng Zhou, Miao Sun, Wenming Wan. Thermo-responsive rheological behavior of borinic acid polymer in dilute solution. RSC Advances 2016,6: 83393-83398.
 (31) Wenming Wan, Andrew. W. Baggett, Fei Cheng, Huina Lin, Shiuyuan Liu, Frieder Jäkle. Synthesis by free radical polymerization and properties of BN-polystyrene and BN-poly(vinylbiphenyl). Chemical Communications 2016, 52: 13616-13619.
 (32) Xiaoyun Zhang, Dongming Liu, Xinhu Lu, Miao Sun, Xiaoli Sun, Wenming Wan. RAFT-polymerization-induced self-Assembly and reorganizations: ultrahigh-molecular-weight polymer and morphology-tunable micro-/nanoparticles in one pot. Macromolecular Rapid Communications 2016, 37: 1735-1741.
 (33) Xiaoli Sun, Dongming Liu, Shuai Pei, Kangkang Li, Wenming Wan. Versatile method to expand the morphology library of block copolymer solution self-assemblies with tubular structures. ACS Macro Letters 2016, 5: 1180-1184.
 (34) 陈伟, 李伟, 朱虎, 曲剑波, 刘建国. 重组大肠杆菌产耐高温Fe-SOD(H29A)的发酵条件优化. 食品与生物技术学报2016, 35(4): 381-386.
 (35) Jianbo Qu, Robert Chapman, Fan Chen, Hongxu Lu, Martina H. Stenzel. Swollen micelles for the preparation of gated, squeezable, pH-responsive drug carriers. ACS Applied Materials & Interfaces 2017, 9 (16): 13865–13874.
 (36) Jianbo Qu, Yuliang Xu, Yu Liu, Yanan Wang, Yuanhong Sui, Jianguo Liu, Xiaojuan Wang. Inherently fluorescent polystyrene microspheres for coating, sensing and cellular Imaging. Colloids and Surfaces B2017, 152: 475-481.
 (37) Lijun Xi, Nenghu Qiao, Zhenchong Zhang, Laihong Yan,Fengbo Li, Jinpeng Hu, Jing Li. Sinorhodobacter hungdaonensis sp nov isolated from activated sludge collected from a municipal wastewater treatment plant. Antonie Van Leeuwenhoek International Journal of General and Molecular Microbiology2017, 110(1): 27-32.
 (38)  Xiaoli Sun, Dongming Liu, Pan Wang, Jialin Tan, Kangkang Li, Li Deng, Wenming Wan. Expanding morphology library of block copolymer self-assemblies with clews of tubules. Chemical Communications2017, 53: 5005-5008.
 (39) Xinhu Lu, Shunshun Li, Chongyu Tian, Maomao Yang, Cheng Li, Yan Zhou, Xiaoli Sun, Jun Zhang, Wenming Wan. Borinic acid polymer: simplified synthesis and enzymatic biofuel cell application. Macromolecular Rapid Communications 2017, 38(6): 1600687.


授权国家发明专利:
(1)曲剑波,宦关生,邵荟荟,刘建国,朱虎,一种亲水性超大孔聚合物微球及其制备方法,2017.02.08,中国,ZL201310475774.5
(2)曲剑波,陈艳丽,宦关生,张晓云,黄方,一种快流速温敏型超大孔生物分离介质的制备方法,2016.01.13,中国,ZL201410142858.1
(3)曲剑波,王晓娟,陈艳丽,宦关生,朱虎,一种聚苯乙烯材料表面亲水改性的方法,2015.10.14,中国,ZL201310315379.0
(4)曲剑波,靖广伦,刘建国,肖梓军,朱虎,一种制备高磁含量壳聚糖纳米球的方法,2014.01.29,中国,ZL201210060861.X
(5)郗丽君,肖梓军,张瑜,朱贤琨,钟骏,吕建仁,一株产聚3-羟基丁酸酯的嗜热菌,2016.11.19,中国,ZL201310705052.4
(6)李静,耿春香,孙秀会,一种对水产养殖环境沉积物中厌氧氨氧化细菌进行定量的方法. 2013.02.13,中国,ZL201210461944.X.